Created from Youtube video: https://www.youtube.com/watch?v=L1W0q1kEof4videoConcepts covered:pharmacokinetics, absorption, distribution, metabolism, excretion
The video explains the concept of pharmacokinetics, which studies how drugs move through the body, focusing on four main processes: absorption, distribution, metabolism, and excretion. It details how drugs are absorbed into the bloodstream, distributed to target cells, metabolized by enzymes, and eventually excreted from the body, while also considering factors like food, other drugs, and anatomical barriers that can influence these processes.
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Pharmacokinetics: How Drugs Move Through the Body
Concepts covered:pharmacokinetics, absorption, distribution, metabolism, excretion
The video explains the concept of pharmacokinetics, which studies how drugs move through the body, focusing on four main processes: absorption, distribution, metabolism, and excretion. It details how drugs are absorbed into the bloodstream, distributed to target cells, metabolized by enzymes, and eventually excreted from the body, while also considering factors like food, other drugs, and anatomical barriers that can influence these processes.
Question 1
Bioavailability affects drug absorption into systemic circulation.
Question 2
How do drugs cross the blood-brain barrier?
Question 3
The first pass effect occurs in the _____.
Question 4
CASE STUDY: A new drug is being developed to treat brain disorders. Researchers are testing its ability to cross the blood-brain barrier.
Which factor affects drug crossing the blood-brain barrier?
Question 5
The first pass effect reduces oral drug bioavailability.
Question 6
What is the role of the hepatic portal system?
Question 7
The process of drug removal from the body is called _____.
Question 8
CASE STUDY: A patient is prescribed a drug that is known to have a high first-pass effect. The doctor is considering alternative administration routes to increase its bioavailability.
Which route increases bioavailability for high first-pass drugs?
Question 9
All drugs can pass the blood-brain barrier.
Question 10
What affects drug bioavailability in the body?
Question 11
Bioavailability refers to the proportion of drug absorbed into _____.
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