Quiz LibraryGeneration of Action Potential | How Action Potential is Generated in neurons, muscles etc?
Created from Youtube video: https://www.youtube.com/watch?v=dZdj124i9Gwvideo
Concepts covered:action potential, depolarization, repolarization, Na-K ATPase pump, positive feedback loop
The video explains the generation of action potential in neurons and muscles, detailing the process from depolarization to repolarization and afterhyperpolarization, emphasizing the roles of Na and K ions and their channels. It also discusses the positive feedback loop involved in action potential generation and the minimal changes in ion concentration gradients, highlighting the importance of the Na-K ATPase pump in restoring these gradients.
Table of Contents1.Understanding Action Potential Generation: A Two-Level Approach2.Understanding Na and K Gradient Maintenance During Action Potentials
chapter
1
Understanding Action Potential Generation: A Two-Level Approach
Concepts covered:action potential, depolarization, repolarization, Na-K ATPase pump, threshold
The chapter explains the generation of an action potential, a rapid change in membrane potential, through a two-level approach. It details the roles of sodium and potassium ions, the phases of depolarization and repolarization, and the importance of the Na-K ATPase pump in restoring ion concentrations, emphasizing the all-or-none nature of action potentials.
Question 1
Action potential is an all or none phenomenon.
Question 2
What is the role of Na-K ATPase pump?
Question 3
The threshold potential for action potential is approximately _____ mV.
Question 4
CASE STUDY: A patient is experiencing muscle weakness and fatigue. Tests show abnormal ion concentrations in their neurons.
What should be corrected to restore action potential?
Question 5
CASE STUDY: A student is simulating action potentials in a lab experiment with varying stimuli strengths.
Select three outcomes of subthreshold stimuli.
Question 6
Repolarization is caused by Na ions entering the cell.
Question 7
How does acetylcholine affect membrane potential?
Question 8
During repolarization, _____ ions move out of the cell.
Question 9
CASE STUDY: A researcher is studying a neuron that fails to generate action potentials despite stimuli.
What could be the reason for failure?
Question 10
Resting membrane potential is positive inside the cell.
Question 11
What defines the 'all or none' phenomenon?
Question 12
The Na-K ATPase pump restores ion concentration after _____ potential.
Question 13
Depolarization involves an influx of Na ions.
Question 14
What occurs during repolarization of the membrane?
Question 15
The action potential starts with _____ of the membrane.
Question 16
Na-K ATPase pump restores ion concentration gradients.
Question 17
What triggers the opening of Na channels?
chapter
2
Understanding Na and K Gradient Maintenance During Action Potentials
Concepts covered:Na-K ATPase pump, action potential, concentration gradients, sodium (Na), potassium (K)
The chapter explains the minimal impact of a single action potential on the sodium (Na) and potassium (K) concentration gradients across the cell membrane, emphasizing that these changes are negligible and require many action potentials to significantly alter the gradients. It highlights the role of the Na-K ATPase pump in maintaining these gradients and clarifies misconceptions about the immediate abolition of these gradients during action potentials.
Question 18
Na-K ATPase pump restores ion gradients after action potentials.
Question 19
What is rare about action potential generation?
Question 20
The Na-K ATPase pump helps restore the _____ gradient.
Question 21
CASE STUDY: A neuroscientist is explaining the action potential to a group of interns. They emphasize the importance of the Na-K gradient in maintaining neuronal function.
What should the interns remember about Na-K gradients?
Question 22
CASE STUDY: During a lab experiment, students observe the action potential in neurons. They are tasked with identifying mechanisms that contribute to repolarization.
Select three mechanisms contributing to repolarization.
Question 23
Na and K gradients are abolished after one action potential.
Question 24
How do Na channels contribute to depolarization?
Question 25
The change in Na and K gradients after one action potential is _____.
Question 26
CASE STUDY: A medical student is studying the action potential process in neurons. They are confused about the role of the Na-K ATPase pump after repeated stimuli.
What should the student understand about Na-K ATPase?
Question 27
Voltage-gated Na channels have activation and inactivation gates.
Question 28
Why is the Na-K gradient change minimal per action potential?
Question 29
During action potential, Na enters and K _____ the cell.
Question 30
Action potential generation involves a positive feedback loop.
Question 31
What maintains Na and K gradients post-action potential?

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