The Complement System, an ancient defense mechanism of over 30 proteins, acts as an effective weapon against invaders by crippling enemies, activating the immune system, and causing lethal damage. Complement proteins, guided by chemistry, form cascades to swiftly neutralize threats, making it a crucial but potentially dangerous component of the immune system.

The Complement System, a sophisticated defense mechanism that evolved over 700 million years ago, consists of over 30 proteins working in harmony to combat intruders. With approximately 15 quintillion proteins present in the body, it serves as a potent weapon against invaders while posing a risk if not regulated by the immune system.

The chapter simplifies the complex mechanisms of The Complement System by focusing on the activation of C3, the initial spark that triggers the complement attack in response to pathogens entering the body.

The complement system efficiently activates C3 proteins to initiate a cascade that leads to the destruction of bacteria and viruses. It orchestrates a series of events that recruit immune cells, create membrane attack complexes, and ultimately neutralize invading pathogens.